A novel polydopamine-based chemiluminescence resonance energy transfer method for microRNA detection coupling duplex-specific nuclease-aided target recycling strategy
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- 作者：Qian Wang ; Bin-Cheng Yin ; binchengyin@ecust.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Bang-Ce Ye ; bcye@ecust.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：MicroRNA detection ; Chemiluminescence resonance energy transfer ; Polydopamine ; Duplex-specific nuclease ; Signal amplification
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：80
- 期：Complete
- 页码：366-372
- 全文大小：1450 K
文摘
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This paper presents a novel signal amplification method for miRNA determination.
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The method combines polydopamine-assisted CRET and DNS-assisted target recycling.
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The method is simple, cost-effective and highly selective for early clinical diagnosis.
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