Glutathione modified Ag₂Te nanoparticles as a resonance Rayleigh scattering sensor for highly sensitive and selective determination of cytochrome C

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• 作者：Shuguang Yan^a ; ^bAuthor Vitae ; Dongyan Deng^aAuthor Vitae ; Li Li^aAuthor Vitae ; Yice Chen^bAuthor Vitae ; Hongjie Song^aAuthor Vitae ; Yi Lv^a ; ^{lvy@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; ^{lvyi03@tsinghua.org.cn" class="auth_mail" title="E-mail the corresponding author}Author Vitae
• 关键词：Ag2Te nanoparticles ; Resonance Rayleigh scattering ; Cytochrome C
• 刊名：Sensors & Actuators: B. Chemical
• 出版年：2016
• 出版时间：2 June 2016
• 年：2016
• 卷：228
• 期：Complete
• 页码：458-464
• 全文大小：1781 K

文摘

Glutathione (GSH) capped Ag₂Te nanoparticles (NPs) were prepared in aqueous solution, and then investigated by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), UV–vis spectra, resonance Rayleigh scattering (RRS) and Fourier transform infrared spectroscopy (FTIR). The results indicated that the prepared GSH-Ag₂Te NPs have good monodispersity, stability and 3–5 nm. Cytochrome C was chosen as a model analyte to study the potential of GSH-Ag₂Te NPs in the RRS analytical application. Under optimal conditions, the RRS intensity of GSH-Ag₂Te NPs was significantly enhanced by interacting with cytochrome C and good linear relationship between the RRS intensity at 365 nm and cytochrome C concentration in the range of 0.08 μg/mL −22.5 μg/mL was found. The limit of detection (LOD) was 0.024 μg/mL. The application in human serum samples indicated that the GSH-Ag₂Te NPs could be a promising candidate probe of RRS biosensors in the future due to their fantastic features.