Severity of mumps disease is related to MMR vaccination status and viral shedding

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• 作者：Sigrid Gouma^a ; ^b ; ^{sigrid.gouma@rivm.nl" class="auth_mail" title="E-mail the corresponding author} ; Susan J.M. Hahné ; ^a ; ^{susan.hahne@rivm.nl" class="auth_mail" title="E-mail the corresponding author} ; Daphne B. Gijselaar^a ; ^{daphne.gijselaar@rivm.nl" class="auth_mail" title="E-mail the corresponding author} ; Marion P.G. Koopmans^a ; ^b ; ^{m.koopmans@erasmusmc.nl" class="auth_mail" title="E-mail the corresponding author} ; Rob S. van Binnendijk^a ; ^{rob.van.binnendijk@rivm.nl" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Mumps disease ; MMR vaccination ; Salivary viral loads ; Viruria ; Parotitis ; Orchitis
• 刊名：Vaccine
• 出版年：2016
• 出版时间：7 April 2016
• 年：2016
• 卷：34
• 期：16
• 页码：1868-1873
• 全文大小：1015 K

文摘

<dl class="listitem" id="list_lis0005"><dt class="label">•dt><dd>

d="par0005">MMR vaccination has a protective effect on severity of mumps disease.

dd><dt class="label">•dt><dd>

d="par0010">Mumps virus detection in urine is a marker for severity of disease.

dd><dt class="label">•dt><dd>

d="par0015">High salivary viral loads are positively associated with systemic mumps disease.

dd><dt class="label">•dt><dd>

d="par0020">MMR vaccine-induced immunological responses affect mumps virus pathogenesis.

dd>dl>