Epidemiology and antimicrobial susceptibility profiles of pathogens causing urinary tract infections in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2010-2013
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- 作者：Shio-Shin Jeana ; b ; Geoffrey Coombsc ; Thomas Lingd ; V. Balajie ; Camilla Rodriguesf ; Hiroshige Mikamog ; Min-Ja Kimh ; Datin Ganeswrie Rajasekarami ; Myrna Mendozaj ; Thean Yen Tank ; Pattarachai Kiratisinl ; Yuxing Nim ; Barry Weinmann ; Yingchun Xuo ; Po-Ren Hsuehp ; hsporen@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Urinary tract infection ; Gram-negative bacteria ; Extended-spectrum β-lactamase ; ESBL ; Susceptibility ; Hospital-acquired
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：47
- 期：4
- 页码：328-334
- 全文大小：637 K
文摘
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A total of 9599 isolates of Gram-negative bacteria (GNB) causing urinary tract infections (UTIs) were collected from 61 centres in 13 countries in the Asia-Pacific region from 2010–2013.
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China, Vietnam, India, Thailand and the Philippines had the highest rates of GNB species producing extended-spectrum β-lactamases (ESBLs) and of cephalosporin resistance.
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ESBL production and hospital-acquired infection significantly compromised the susceptibility of E. coli and K. pneumoniae to ciprofloxacin, levofloxacin and most β-lactams, with the exception of imipenem and ertapenem.
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