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Exercise, but not antioxidants, reversed ApoE4-associated motor impairments in adult GFAP-ApoE mice
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Profiling of motor behavior of adult GFAP-ApoE3 and GFAP-ApoE4 mice.

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Determination of whether exercise training and antioxidant intake combined can improve further motor dysfunction.

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Exercise was more efficient at improving motor function than antioxidants alone.

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Combination of exercise and antioxidant did not lead to further beneficial effect, and had a moderate antagonistic interaction on strength measurements.

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