Aromatase can be visualized in vivo using PET and [¹¹C]vorozole.

Aromatase concentrations are slightly higher in males than in females.

Highest brain concentrations are found in rat and monkey amygdala and human thalamus.

Liver has high non specific uptake of radioactivity in all species following [¹¹C]vorozole administration.

Aromatase PET may improve diagnosis and treatment in brain disorders and cancer.