NaHCO₃-Buffered Lidocaine Gel for Outpatient Rigid Cystoscopy in Men

详细信息    查看全文

• 作者：Hong Li ; MDAuthor Vitae ; Yanxin Cheng ; MDAuthor Vitae ; Jun Li ; MDAuthor Vitae ; Yongxue Chen ; MDAuthor Vitae ; Jinge Yuan ; MDAuthor Vitae ; Shuhong Yang ; MSAuthor Vitae ; Huiqiao Shi ; MSAuthor Vitae ; Wenpin Li ; MDAuthor Vitae ; Shijie Yang ; MDAuthor Vitae ; Wei Wang ; MDAuthor Vitae ; Guanjie Xu ; MDAuthor Vitae ; Senming Zhao ; MD ; ^{senming63@hotmail.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae
• 关键词：topical anesthesia ; alkalization ; lidocaine gel ; cystoscopy
• 刊名：Journal of PeriAnesthesia Nursing
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：31
• 期：2
• 页码：154-157
• 全文大小：90 K

文摘

The purpose of this study was to explore the effect of NaHCO₃-buffered lidocaine gel as a topical anesthetic agent for pain relief for rigid cystoscopy.

Design

Prospective randomized controlled trial.

Methods

ASA I-II male patients undergoing rigid cystoscopy randomly received 10 mL 2% Carbocaine lidocaine gel with 1 mL 0.9% saline (group 1) or 1 mL 5% NaHCO₃ solution (group 2). After 3 minutes exposure, the cystoscope was inserted into the urethra. On receiving the gel, cystoscope insertion, and intravesical observation, pain score was recorded using the visual analog scale.

Findings

The gel pH with or without NaHCO₃ was 7.20 and 6.41, respectively. The concentration of soluble lidocaine in the gel was stable for 24 hours or more. The visual analog scale score in group 2 was significantly lower (1.3 ± 0.9) than in group 1 (5.28 ± 1.99). No adverse effects were recorded.

Conclusion

Alkalized lidocaine gel resulted in successful analgesia for rigid cystoscopy in men without adverse effects.