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A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1
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文摘

MiR-552 suppresses CYP2E1 expression at both transcriptional and translational levels.

MiR-552 targets the loop hairpin of the cruciform structure in CYP2E1 promoter.

MiR-552 inhibits SMARCE1 binding to CYP2E1 promoter and CYP2E1 transcription.

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