p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions
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- 作者：Qian Cong1 ; 8 ; Hao Jia1 ; 2 ; 8 ; Soma Biswas1 ; Ping Li1 ; Shoutao Qiu1 ; Qi Deng1 ; Xizhi Guo1 ; Gang Ma1 ; Jenny Fang Ling Chau3 ; Yibin Wang4 ; Zhen-Lin Zhang5 ; Xinquan Jiang6 ; Huijuan Liu1 ; liuhj@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Baojie Li1 ; 7 ; libj@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 刊名：Stem Cell Reports
- 出版年：2016
- 出版时间：12 April 2016
- 年：2016
- 卷：6
- 期：4
- 页码：566-578
- 全文大小：2991 K
文摘
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p38α deletion in Prx1+ BM-MSCs led to osteoporosis and cartilage anomaly
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p38α controls proliferation and tri-lineage differentiation of Prx1+ BM-MSCs
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p38α regulates osteoclastogenesis through OPG production by BM-MSCs
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The BM-MSC p38-OPG axis participates in estrogen deficiency-induced osteoporosis
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