Three New C₂₁ Steroidal Glycosides from Roots of Cynanchum otophyllum

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• 作者：Yi-bin Zhao ; ^{15912141693@139.com" class="auth_mail" title="E-mail the corresponding author} ; Yue-mao Shen ; Hong-ping He ; Zhi-zhi Du ; Quan-zhang Mu ; Xiao-jiang Hao
• 关键词：Asclepiadaceae ; Cynanchum otophyllum ; C21 steroidal glycoside
• 刊名：Chinese Herbal Medicines
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：8
• 期：2
• 页码：189-194
• 全文大小：513 K

文摘

To investigate the chemical structures of glycosides in the roots of Cynanchum otophyllum (Asclepiadaceae) and to find new glycosides.

Methods

The total glycosides in the roots of C. olophyllum were separated by silica gel column chromatography. The structures of the resulting compounds were determined by NMR and FAB-MS spectra.

Results

Three C21 steroidal glycosides were separated. Their structures were determined as caudatin 3-O-(4-O-methyl-β-D-cymaropyranosyl)-(1→4)-α-D-oleandropyranosyl-(1→4)-β-D-glucopyranosyl-(1→4)-α-L-rhamnopyranoside (1), caudatin 3-O-β-D-digitoxopyranosyl-(1→4)-α-D-oleandropyranosyl-(1→4)-β-Ddiginopyranosyl-(1→4)-β-D-glucopyranoside (2), and caudatin 3-O-β-D-diginopyranosyl-(1→4)-α-D-oleandropyranosyl-(1→4)-α-D-oleandropyranosyl-(1→4)-β-D-glucopyranoside (3), respectively.

Conclusion

Glycosides 1–3 are new compounds.