Therapeutic potential of cysteine-rich protein 61 in rheumatoid arthritis
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- 作者：Tao Xua ; 1 ; Ying-hua Hea ; 1 ; Ming-quan Wangb ; 1 ; Hong-wei Yaoa ; Ming-ming Nic ; Lei Zhanga ; Xiao-ming Menga ; Cheng Huanga ; Yun-xuan Ged ; Jun Lia ; lj@ahmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; ahmuxutao@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cyr61 ; cysteine-rich protein 61 ; RA ; rheumatoid arthritis ; IL-17 ; interleukin-17 ; ECM ; extracellular matrix ; CTGF ; connective tissue growth factor ; IGFBP ; insulin-like growth factor binding protein domain ; VWC ; von Willebrand type C repeat ; TSP-1 ; thrombospondin type I domain ; CT ; carboxyl terminal ; HSPGs ; heparan sulfate proteoglycans ; TrkA ; neurotrophic tyrosine kinase receptor type 1 ; LRPs ; low-density lipoprotein receptor-related proteins ; BMPs ; bone morphogenetic proteins ; TGF-β ; tumor grow
- 刊名：Gene
- 出版年：2016
- 出版时间：30 October 2016
- 年：2016
- 卷：592
- 期：1
- 页码：179-185
- 全文大小：477 K
文摘
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Cyr61 is a pro-inflammatory molecule that is able to affect inflammatory responses.
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Cyr61 may be a useful marker of the inflammatory process in RA.
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Cyr61 in the pathogenesis of RA
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Therapeutic implications for targeting Cyr61 in RA
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