The core structure of a Dendrobium huoshanense polysaccharide required for the inhibition of human lens epithelial cell apoptosis
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- 作者：Xue-Qiang Zhaa ; b ; 1 ; 2 ; zhaxueqiang@hfut.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yuan-Yuan Dengc ; 2 ; Xiao-Long Lib ; Jing-Fei Wangb ; Li-Hua Panb ; Jian-Ping Luob ; 1 ; jianpingluo@hfut.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dendrobium huoshanense ; Polysaccharides ; Core structure ; Human lens epithelial cell ; Apoptosis
- 刊名：Carbohydrate Polymers
- 出版年：2017
- 出版时间：2 January 2017
- 年：2017
- 卷：155
- 期：Complete
- 页码：252-260
- 全文大小：2885 K
文摘
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An active polysaccharide (DHPD1) was isolated from Dendrobium huoshanense.
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DHPD1 was shown to inhibit the apoptosis of human lens epithelial cells.
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The active core domain of DHPD1 was prepared using pectinase hydrolyzation.
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The basic structure features of the core domain of DHPD1 were characterized.
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DHPD1 and its core domain prevent cell apoptosis via alleviating cell inflammation.
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