Right ventricular (RV) dysfunction has proved to be an i
mportant predictor of
morbidity and
mortality in patients with pul
monary e
mbolis
m (PE). Tricuspid annular plane systolic excursion (TAPSE) is one of the para
meters that have been validated as predictor of outco
mes. The ai
m of our study was to evaluate the perfor
mance (sensitivity and specificity) of high-sensitivity cardiac troponin T (hs-cTnT) to predict RV dysfunction defined as TAPSE < 16
mm.
Methods
We conducted a single-center retrospective analysis of 40 patients prospectively included. Median age was 66 years (59–76) and PESI score was 81 (67–100).
Results
Right ventricular dysfunction was present in 30% of the patients and was associated with higher median troponin values (33.5 ng/L vs 16 ng/L; m>Pm>= .03). A logarithmic relation was observed between hs-cTnT and lower TAPSE values (m>rm>2= 0.36; m>Pm>< .0001). The area under the ROC curve of hs-cTnT to predict RV dysfunction was 0.77 (0.63–0.92).
Conclusion
hs-cTnT is a biomarker with good performance to identify RV dysfunction in PE.