GPX1 Pro198Leu polymorphism and GSTM1 deletion do not affect selenium and mercury status in mildly exposed Amazonian women in an urban population
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- 作者：Ariana V. Rochaa ; Bá ; rbara Rita Cardosoa ; b ; barbara.rita@florey.edu.au" class="auth_mail" title="E-mail the corresponding author ; Bruna Zavarizea ; Kaluce Almondesa ; Isabella Bordonc ; Dominic J. Hareb ; d ; Dé ; borah Inê ; s Teixeira Favaroc ; Silvia Maria Franciscato Cozzolinoa
- 关键词：Selenium ; Mercury detoxification ; Amazon ; Exposure biology ; GPX1 polymorphism ; GSTM1 deletion
- 刊名：Science of the Total Environment
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：571
- 期：Complete
- 页码：801-808
- 全文大小：756 K
文摘
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Study of effects of GPX1 and GSTM polymorphisms on mercury levels in an urban female population in the Amazon
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Analysis of selenium in erythrocytes and mercury in hair, with oxidative stress markers and genotyping of GPX1 and GSTM
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High prevalence of selenium deficiency despite ready access to selenium-rich produce
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Low levels of mercury toxicity despite historically high exposures in this region
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Polymorphisms to GPX1 and GSTM do not appear to influence mercury levels in mildly-exposed populations
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