A convenient purification method for metal nanoclusters based on pH-induced aggregation and cyclic regeneration and its applications in fluorescent pH sensors

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• 作者：Huayu XiongAuthor Vitae ; Wei WangAuthor Vitae ; Jichao LiangAuthor Vitae ; Wei WenAuthor Vitae ; Xiuhua ZhangAuthor Vitae ; Shengfu Wang ; ^{wangsf@hubu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; ^{wangsf302@163.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae
• 关键词：Metal nanoclusters ; Fluorescent pH sensor ; Fluorescence ; Purification ; Regeneration
• 刊名：Sensors & Actuators: B. Chemical
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：239
• 期：Complete
• 页码：988-992
• 全文大小：1135 K

文摘

Herein, we report a convenient approach to purify water-soluble bovine serum albumin (BSA)-capped metal nanoclusters by pH-induced precipitation under acidic conditions. The fluorescence of metal nanoclusters could be completely recovered upon the re-dispersion of nanoparticles into basic media. BSA metal nanoclusters have been prepared to monitor pH at highly acidic medium. When pH decreased, the fluorescence of the nanoclusters under a UV lamp decreased and completely disappeared after pH 4. And a fluorescent pH sensor for pH monitoring has been developed based on the “OFF–ON” signal switch of the gold clusters agarose hydrogel.