A terminal-block strategy for the amplified detection of DNA-break events
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- 作者：Jiepei Caoa ; 1Author Vitae ; Hai Shia ; b ; 1Author Vitae ; Xiaoxia ChenaAuthor Vitae ; Zihan WangaAuthor Vitae ; Yaoyao ChenaAuthor Vitae ; Yongqian Shuc ; Author Vitae ; Xiaoli Zhua ; xiaolizhu@shu.edu.cn" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：DNA break ; Rolling circle amplification ; Fenton reaction ; Nicking endonuclease
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：238
- 期：Complete
- 页码：331-336
- 全文大小：1768 K
文摘
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A novel strategy is developed for the detection of DNA-break events.
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Rolling circle amplification is integrated to improve the sensitivity.
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Both double-strand break and single-strand break can be well detected.
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