miRNA-216 and miRNA-499 target cyb561d2 in zebrafish in response to fipronil exposure

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miRNA-216 and miRNA-499 target cyb561d2 in zebrafish in response to fipronil exposure

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作者：Yongyong Zhou^a ; ¹ ; Hannian Huang^b ; ¹ ; Kai Zhang^a ; Xianfeng Ding^a ; Longlue Jia^a ; Liang Yu^c ; Guonian Zhu^c ; Jiangfeng Guo^a ; ^{603422689@qq.com" class="auth_mail" title="E-mail the corresponding author}
关键词：MicroRNA ; miR-155 ; miR-216b ; miR-499 ; cyb561d2 ; Toxicity ; Fipronil ; Zebrafish
刊名：Environmental Toxicology and Pharmacology
出版年：2016
出版时间：July 2016
年：2016
卷：45
期：Complete
页码：98-107
全文大小：1992 K

文摘

•: m>miR-216bm> and m>miR-499m> were interacted with m>cyb561d2m>3′-untranslated regions (3′-UTR).
•: m>miR-216bm> and m>miR-499m> were downregulated upon stimulation of fipronil.
•: The ectopic expression of m>miR-216bm> and m>miR-499m> could regulate cyb561d2.
•: m>miR-216bm> and m>miR-499m> could be considered as potential biomarker for fipronil toxicity.

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