Optimal digital filters for analyzing the mid-latency auditory P50 event-related potential in patients with Alzheimer’s disease
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- 作者：Sara Liljandera ; sara.liljander@hus.fi" class="auth_mail" title="E-mail the corresponding author ; sara.liljander@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Anu Holmb ; anu.holm@satadiag.fi" class="auth_mail" title="E-mail the corresponding author ; Petra Keski-Sä ; nttic ; petra.keski-santti@terveystalo.com" class="auth_mail" title="E-mail the corresponding author ; Juhani V. Partanena ; juhani.v.partanen@hus.fi" class="auth_mail" title="E-mail the corresponding author
- 关键词：Event-related potential ; P50 ; Sensory gating ; Alzheimer&rsquo ; s disease ; Digital filter ; Filter distortion
- 刊名：Journal of Neuroscience Methods
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：266
- 期：Complete
- 页码：50-67
- 全文大小：2476 K
文摘
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Filtering may severely distort the time-domain representations of ERP waveforms.
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Inappropriate filter parameters can lead to false conclusions.
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Careful filter design results in improved signal-to-noise ratio of ERP waveforms.
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The effect of different filter settings on the P50 component is investigated.
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The results provide evidence of optimal filters for P50 sensory gating analyses.
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