Construction of reduction-responsive photosensitizers based on amphiphilic block copolymers and their application for photodynamic therapy
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- 作者：Qiang Zhou ; Lei Xu ; Feng Liu ; Weian Zhang ; wazhang@ecust.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Block copolymer ; Self-assembly ; Photodynamic therapy
- 刊名：Polymer
- 出版年：2016
- 出版时间：5 August 2016
- 年：2016
- 卷：97
- 期：Complete
- 页码：323-334
- 全文大小：2177 K
文摘
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Reduction-responsive POEGMA-b-PTPPC6SAM block copolymers were synthesized via RAFT polymerization.
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POEGMA-b-PTPPC6SAM block copolymers could self-assemble into spherical micelles and vesicles.
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POEGMA-b-PTPPC6SAM micelles had a higher photo-toxicity with a lower IC50 (porphyrin concentration below 3 μg/mL).
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