A polyamidoamne dendrimer functionalized graphene oxide for DOX and MMP-9 shRNA plasmid co-delivery
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- 作者：Yaming Gua ; Yizhen Guoa ; Changyong Wangb ; Jiake Xuc ; Jianping Wud ; Thomas Brett Kirkd ; Dong Maa ; tmadong@jnu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Wei Xuea ; weixue_jnu@aliyun.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Graphene oxide ; Dendrimer ; DOX ; MMP-9 shRNA plasmid ; Co-delivery
- 刊名：Materials Science & Engineering C
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：70
- 期：part_P1
- 页码：572-585
- 全文大小：3276 K
文摘
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PAMAM-functionalized GO was prepared and used to co-deliver DOX and MMP-9 shRNA plasmid.
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It showed an effective delivery of DOX and MMP-9 to MCF-7 cells.
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The co-loaded PAMAM-GO suggested a potential application in cancer therapy.
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