Phytochemical mediated-modulation of the expression and transporter function of breast cancer resistance protein at the blood-brain barrier: An in-vitro study
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- 作者：Manjit Kaur ; Raj K.S. Badhan ; r.k.s.badhan@aston.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：ABC ; ATP-binding cassette ; AhR ; aryl hydrocarbon receptor ; BBB ; blood-brain barrier ; BCRP ; breast cancer resistance protein ; BCSFB ; blood-CSF-barrier ; CNS ; central nervous system ; PhA ; pheophorbide A ; TEER ; trans-endothelial electrical resistance
- 刊名：Brain Research
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：1654
- 期：part_PA
- 页码：9-23
- 全文大小：2398 K
文摘
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Naringin and quercetin induced BCRP expression and function.
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Curcumin and 17-β-estradiol down-regulated BCRP expression and function.
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2,6,4-trimethoflavone is a potent inhibitor of BCRP function.
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