Accurate annotation of protein-coding genes in mitochondrial genomes
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- 作者：Marwa Al Araba ; b ; h ; marwa@bioinf.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author ; Christian Hö ; ner zu Siederdissena ; b ; c ; choener@bioinf.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author ; Kifah Touth ; ktout@ul.edu.lb" class="auth_mail" title="E-mail the corresponding author ; Abdullah H. Sahyouna ; b ; h ; i ; abdullah.sahyoun@tron-mainz.de" class="auth_mail" title="E-mail the corresponding author ; Peter F. Stadlera ; b ; c ; d ; e ; f ; g ; studla@bioinf.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author ; Matthias Bernta ; j ; bernt@informatik.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Protein coding genes ; Metazoa ; Mitochondrial DNA ; Annotation ; Hidden Markov models
- 刊名：Molecular Phylogenetics and Evolution
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：106
- 期：Complete
- 页码：209-216
- 全文大小：996 K
文摘
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An automated pipeline for fast de-novo annotation of mitochondrial protein-coding genes is presented.
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The method generates taxon-specific enhanced multiple sequence alignments (MSA) and corresponding HMMs.
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Automatic frameshift correction method.
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Detailed analysis of the frameshifts in nad3 of the Testudines-Archosauria.
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