LDL-C/apoB and HDL-C/apoA-1 ratios predict incident chronic kidney disease in a large apparently healthy cohort
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- 作者：Ji Cheol Baea ; Ji Min Hana ; Sam Kwona ; Jae Hwan Jeeb ; Tae Yang Yuc ; Moon Kyu Leec ; Jae Hyeon Kimc ; d ; jaehyeon@skku.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chronic kidney disease ; Dyslipidemia ; Estimated glomerular filtration rate ; Triglycerides to high-density lipoprotein cholesterol ratio ; Low-density lipoprotein cholesterol ; Apolipoprotein
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：251
- 期：Complete
- 页码：170-176
- 全文大小：707 K
文摘
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Baseline TG, HDL-C levels and TG/HDL-C ratio predicted subsequent development of CKD.
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A significant longitudinal association was found between incident CKD and the baseline LDL- C/apoB and HDL-C/apoA-1 ratios.
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The risk for incident CKD was not associated with baseline LDL-C, non-HDL-C, apoB, apoA-I, or the apoB/apoA-I ratio.
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Particle size of HDLs and LDLs may contribute to the development of CKD.
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