Reaction of 1-vinylpyrrole-2-carbaldehydes with phosphorus pentachloride: a stereoselective synthesis of E-2-(2-dichloromethylpyrrol-1-yl)vinylphosphonyl dichlorides

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• 作者：M.Yu. Dmitrichenko^a ; ^† ; ; A.V. Ivanov^b ; I.A. Bidusenko^b ; I.A. Ushakov^b ; A.I. Mikhaleva^b ; B.A. Trofimov^b ; ^{boris_trofimov@irioch.irk.ru}
• 关键词：1-Vinylpyrrole-2-carbaldehydes ; Phosphorus pentachloride ; E-2-(2-Dichloromethylpyrrol-1-yl)vinylphosphonyl dichlorides ; E-2-(2-Dichloromethylpyrrol-1-yl)vinylphosphonium hexachlorophosphates
• 刊名：Tetrahedron Letters
• 出版年：2011
• 出版时间：23 March 2011
• 年：2011
• 卷：52
• 期：12
• 页码：1317-1319
• 全文大小：433 K

文摘

1-Vinylpyrrole-2-carbaldehydes react with phosphorus pentachloride (benzene, 10–15 °C) to afford E-2-(2-dichloromethylpyrrol-1-yl)vinylphosphonium hexachlorophosphates in up to 85 % yield, which after treatment with SO₂ (benzene, rt) are converted into E-2-(2-dichloromethylpyrrol-1-yl)vinylphosphonyl dichlorides in 50–75 % yields.