The gene expression profile of non-cultured, highly purified human adipose tissue pericytes: Transcriptomic evidence that pericytes are stem cells in human adipose tissue
详细信息 查看全文
- 作者：Lindolfo da Silva Meirellesa ; b ; lindolfomeirelles@gmail.com" class="auth_mail" title="E-mail the corresponding author ; lindolfomeirelles@ulbra.edu.br" class="auth_mail" title="E-mail the corresponding author ; Virgí ; nia Mara de Deus Wagatsumaa ; Tathiane Maistro Maltaa ; Patrí ; cia Viana Bonini Palmaa ; Amé ; lia Goes Araú ; joc ; Rodrigo Alexandre Panepuccic ; Wilson Araú ; jo Silva ; Jr.a ; d ; Simone Kashimaa ; Dimas Tadeu Covasa ; e
- 关键词：AT ; adipose tissue ; ncATPCs ; non-cultured adipose tissue-derived pericytes ; ATMSCs ; adipose tissue-derived mesenchymal stromal cells ; ATMSCs 18 PM ; ATMSCs from donor 18 cultured in pericyte medium ; BMMSCs ; bone marrow mesenchymal stromal cells ; cATPCs ; cultured adipose tissue-derived pericytes ; cATPCs 1&ndash ; 3 DME10 ; cATPCs from donors 1&ndash ; 3 cultured in DMEM/10 ; DMEM/10 ; Dulbecco's Modified Eagle's Medium (DMEM) containing 10% (v/v) fetal bovine serum ; DPSCs ; dental pulp stem cells ; ECs ; en
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：10 December 2016
- 年：2016
- 卷：349
- 期：2
- 页码：239-254
- 全文大小：5687 K
文摘
- •
Non-cultured adipose tissue-derived human pericytes (ncATPCs) exhibit a distinctive gene expression signature.
- •
ncATPCs express key adipose tissue stem cell genes previously described in vivo in mice.
- •
ncATPCs express message for anti-proliferative and antiangiogenic molecules.
- •
Most ncATPC-specific transcripts are absent in culture-expanded pericytes or ATMSCs
- •
Gene expression changes ncATPCs undergo as they acquire a cultured ATMSC phenotype are pointed out.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |