The impact of inflammation on respiratory plasticity
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- 作者：Austin D. Hockera ; Jennifer A. Stokesb ; Frank L. Powellb ; Adrianne G. Huxtablea ; huxtable@uoregon.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：CNS ; central nervous system ; DAMPs ; danger-associated molecular patterns ; LPS ; lipopolysaccharide ; CFA ; complete Freund's adjuvant ; Poly(I ; C) ; Polyinosinic ; polycytidylic acid ; TLR ; toll-like receptors ; BBB ; blood brain barrier ; PHD ; prolyl hydroxylases ; IKK-β ; IκB kinase ; SNI ; spared nerve injury ; CIH ; chronic intermittent hypoxia ; LTF ; long-term facilitation ; CSH ; chronic sustained hypoxia ; IL ; interleukin ; TNF ; tumor necrosis factor ; COX ; cyclyooxengenase ; PGE ; prostaglandin ; pLTF ; phrenic lon
- 刊名：Experimental Neurology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：287
- 期：part_P2
- 页码：243-253
- 全文大小：617 K
文摘
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Reviews the impact of inflammation on different forms of respiratory plasticity
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Inflammation contributes to chronic hypoxia induced oxygen sensitivity.
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Inflammation abolishes phrenic long-term facilitation.
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Highlights gaps in knowledge and relevance to clinical conditions and treatments.
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