The role of MSP I CYP1A1 gene polymorphism in the development of uterine fibroids

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• 作者：Marco Antô ; nio Bar&#xe3 ; o ; Emerson Oliveira ; Mariano Tamura Vieira Gomes ; Ismael Dale Cotrim Guerreiro da Silva ; Marair Gracio Ferreira Sartori ; Manoel Jo&#xe3 ; o Batista Castello Gir&#xe3 ; o ; Rodrigo de Aquino Castro
• 关键词：Leiomyoma ; polymorphism ; CYP1A1
• 刊名：Fertility and Sterility
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：94
• 期：7
• 页码：2783-2785
• 全文大小：72 K

文摘

The cytochrome P-450 1A1 (CYPA1A) gene plays an important role in the metabolization of estrogen and is therefore a candidate marker for fibroids. In a case-control study, we were unable to demonstrate any association between MSP I CYP1A1 polymorphism and the risk of leiomyoma in Brazilian women.