A dual-responsive supramolecular amphiphile based on cucurbit[7]uril/butyrylcholine host-guest molecular recognition

详细信息    查看全文

• 作者：Rener Chen^a ; Haining Gu^b ; Fangli Qiu^a ; Qizhong Zhou^a ; ^{qizhongchou@tzc.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Rongrong Li^a ; Yuyuan Ye^a ; Yuguo Zhuang^a ; Jie Zhang^a ; Huajiang Jiang^a ; ^{jhj@tzc.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Cucurbit[7]uril ; Butyrylcholine ; host&ndash ; guest molecular recognition ; Dual-responsive ; Supramolecular amphiphile
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：1 September 2016
• 年：2016
• 卷：72
• 期：35
• 页码：5290-5294
• 全文大小：943 K

文摘

A host–guest molecular recognition is reported between cucurbit[7]uril and butyrylcholine with the driving forces of hydrophobic and charge-dipole interactions. On the basis of this recognition, an enzyme- and photo-responsive supramolecular amphiphile is fabricated, which self-assembles into vesicles in aqueous solution. The assembly and disassembly of vesicles are successfully employed in stimuli-triggered releases of doxorubicin hydrochloride.