Antidiabetic activity and chemical constituents of the aerial parts of Heracleum dissectum Ledeb.
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- 作者：Hailong Zhanga ; Yaping Sua ; b ; Xinrui Wanga ; Jie Mia ; Yayu Huoa ; Zhigang Wangc ; Ying Liud ; Yang Gaoa ; gaoyangyang@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glucose (PubChem CID 5793) ; Streptozotocin (PubChem CID 29327) ; Gliclazide (PubChem CID 3475) ; Metformin (PubChem CID 4091) ; Acarbose (PubChem CID 41774) ; Ascorbic acid (PubChem CID 54670067) ; DPPH (PubChem CID 2735032)
- 刊名：Food Chemistry
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：214
- 期：Complete
- 页码：572-579
- 全文大小：981 K
文摘
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Antidiabetic research on the aerial parts of Heracleum dissectum in vivo and in vitro.
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The aerial parts of H. dissectum methanol extract had potent antidiabetic activity.
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The active part was petroleum ether fraction.
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The main components of the active part were coumarins.
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A possible mechanism of antidiabetic action in vivo was proposed.
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