MiR-22 promotes porcine reproductive and respiratory syndrome virus replication by targeting the host factor HO-1
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- 作者：Shuqi Xiaoa ; b ; 1 ; xiaoshuqi@nwsuaf.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Taofeng Dua ; b ; 1 ; taofengdu@126.com" class="auth_mail" title="E-mail the corresponding author ; Xue Wanga ; b ; wx0507@126.com" class="auth_mail" title="E-mail the corresponding author ; Huaibao Nia ; b ; tianhexiaoyudian@163.com" class="auth_mail" title="E-mail the corresponding author ; Yunhuan Yana ; b ; 1107867089@qq.com" class="auth_mail" title="E-mail the corresponding author ; Na Lia ; b ; lina330077@163.com" class="auth_mail" title="E-mail the corresponding author ; Chong Zhanga ; b ; leofighting@163.com" class="auth_mail" title="E-mail the corresponding author ; Angke Zhanga ; b ; zhangangke1112@126.com" class="auth_mail" title="E-mail the corresponding author ; Jiming Gaoa ; b ; jimingao2006@163.com" class="auth_mail" title="E-mail the corresponding author ; Hongliang Liua ; b ; liuhongliang55@126.com" class="auth_mail" title="E-mail the corresponding author ; Fengxing Pua ; b ; puyuchen617@163.com" class="auth_mail" title="E-mail the corresponding author ; Gaiping Zhanga ; c ; Zhanggaiping2003@163.com" class="auth_mail" title="E-mail the corresponding author ; En-Min Zhoua ; b ; zhouem@nwsuaf.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：miRNA ; PRRSV ; HO-1 ; Post-transcriptional regulation ; Virus-cell interaction
- 刊名：Veterinary Microbiology
- 出版年：2016
- 出版时间：30 August 2016
- 年：2016
- 卷：192
- 期：Complete
- 页码：226-230
- 全文大小：922 K
文摘
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PRRSV infection induces miR-22 expression.
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MiR-22 directly interacts with the antiviral host factor HO-1.
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Expression levels of HO-1 and miR-22 are inversely correlated.
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MiR-22 promotes PRRSV replication by targeting the antiviral host factor HO-1.
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