Antiviral therapy of hepatitis delta virus infection — progress and challenges towards cure
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- 作者：Anika Wranke1 ; Heiner Wedemeyer1 ; 2 ; 3 ; 4 ; Wedemeyer.Heiner@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Opinion in Virology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：20
- 期：Complete
- 页码：112-118
- 全文大小：407 K
文摘
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Hepatitis delta is the most severe form of chronic viral hepatitis.
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Pegylated interferon alpha is currently the only recommended treatment option.
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PEG-IFNa therapy leads to a virological response in about 25–30% of patients.
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A beneficial clinical long-term outcome of IFNa-based therapy has been suggested.
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New treatment strategies are in clinical development.
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