On the PdCl₂-catalyzed synthesis of allylic azides and allylic sulfonamides from homoallylic alcohols

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• 作者：Jean  ; Le Bras ; Jacques  ; Muzart  ; ;   ; ^{jacques.muzart@univ-reims.fr}
• 关键词：Homoallylic alcohol ; Isomerization ; Allylic alcohol ; Aminopalladation
• 刊名：Tetrahedron Letters
• 出版年：2011
• 出版时间：12 October 2011
• 年：2011
• 卷：52
• 期：41
• 页码：5217-5219
• 全文大小：365 K

文摘

According to experimental and literature data, the one-pot formation of allylic azides or sulfonamides from catalytic amounts of PdCl₂, homoallylic alcohols and TMSN₃ or TsNH₂ occurs through CC migration followed by regioselective nucleophilic addition on the Pd^II-activated CC bond and ¦Â-OH elimination.