Multivariable optimization of the micellar system for the ionic liquid-modified MEKC separation of phenolic acids
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- 作者：Lei Liu1 ; Bin Wu1 ; Ke Liu ; Chao-Ran Li ; Xu Zhou ; Ping Li ; liping2004@126.com" class="auth_mail" title="E-mail the corresponding author ; ; Hua Yang ; 104yang104@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mixture design ; Micellar electrokinetic chromatography ; Ionic liquids ; Additives ; Phenolic acids
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：126
- 期：Complete
- 页码：1-8
- 全文大小：1460 K
文摘
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An ionic liquid-modified MEKC method was proposed.
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The addition of ILs in BGE could significantly improve the resolution of target analysts.
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The micellar system was optimized by using a D-optimal design.
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A 16-run experimental plan was carried out.
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Eight phenolic acids were well separated in 10 min.
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