Cerium(IV) oxide as a neutral catalyst for aldehyde-induced decarboxylative coupling of l-proline with triethyl phosphite and nitromethane

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• 作者：Habib Firouzabadi ; Nasser Iranpoor ; Arash Ghaderi ; Maryam Ghavami
• 关键词：CeO2 ; Three-component reaction ; Proline ; Cycloaddition ; Decarboxylative coupling
• 刊名：Tetrahedron Letters
• 出版年：2012
• 出版时间：10 October, 2012
• 年：2012
• 卷：53
• 期：41
• 页码：5515-5518
• 全文大小：405 K

文摘

The application of cerium(IV) oxide (CeO₂) as a neutral and heterogeneous catalyst for aldehyde-induced decarboxylative coupling of l-proline with triethyl phosphite and nitromethane is described. In addition, a [3+2] cycloaddition reaction of the in situ generated 1,3-dipolar intermediate with benzaldehyde in the absence of a nucleophile is also reported.