Enhancing gilthead seabream immune status and protection against bacterial challenge by means of antigens derived from Vibrio parahaemolyticus

详细信息    查看全文

• 作者：Martha Reyes-Becerril^a ; Crystal Guluarte^a ; Diana Ceballos-Francisco^b ; Carlos Angulo^a ; ^{eangulo@cibnor.mx} ; M. Á ; ngeles Esteban^b ; ^{aesteban@um.es}
• 关键词：Lysate ; ToxA ; PirA-like ; Vibrio parahaemolyticus ; Mucosal immunity ; Gene expression ; Gilthead seabream
• 刊名：Fish & Shellfish Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：Complete
• 页码：205-218
• 全文大小：1691 K
• 卷排序：60

文摘

The immunostimulant effects of lysate and ToxA from Vibrio parahaemolyticus have been evaluated. Fish immunized with lysate and ToxA had 100% and 50% of survival, respectively, when challenged with the pathogen. Immune parameters in skin mucus were enhanced by intraperitoneal immunization. Injection of lysate or ToxA to fish has a protective effect on the deleterious effects caused by V. parahaemolyticus. Lysate and ToxA could be considered as potent preventive antigens to vibriosis for gilthead seabream.