Randomized study of the clinical effects of ω-3 fatty acid-containing enteral nutrition support during neoadjuvant chemotherapy on chemotherapy-related toxicity in patients with esophageal cancer
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- 作者：Hiroshi Miyata ; M.D.a ; b ; Hmiyata@gesurg.med.osaka-u.ac.jp ; Masahiko Yano ; M.D.b ; Takushi Yasuda ; M.D.c ; Makoto Yamasaki ; M.D.a ; Kohei Murakami ; M.D.a ; Tomoki Makino ; M.D.a ; Kohei Nishiki ; M.D.c ; Keijiro Sugimura ; M.D.b ; Masaaki Motoori ; M.D.b ; Osamu Shiraishi ; M.D.c ; Masaki Mori ; M.D.a ; Yuichiro Doki ; M.D.a
- 关键词：Esophageal cancer ; Chemotherapy ; Enteral nutrition ; Toxicity ; Adverse effect ; ω-3 fatty acid
- 刊名：Nutrition
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：33
- 期：Complete
- 页码：204-210
- 全文大小：720 K
- 卷排序：33
文摘
Little is known about the effect of ω-3 fatty acids on reducing chemotherapy-related toxicities. A randomized study was conducted to compare ω-3–rich enteral nutrition (EN) with ω-3–poor EN in patients undergoing cisplatin-based chemotherapy. ω-3–rich EN reduced the incidence of chemotherapy-related mucosal toxicities and had a hepatoprotective effect during chemotherapy.