Biomarkers associated with disease severity in allergic and nonallergic asthma

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• 作者：Selene Baos^a ; ^b ; David Calzada^a ; Luc&iacute ; a Cremades^a ; Joaqu&iacute ; n Sastre^b ; ^c ; Joaqu&iacute ; n Quiralte^d ; Fernando Florido^e ; Carlos Lahoz^a ; ^b ; Blanca Cá ; rdaba^a ; ^b ; ^{bcardaba@fjd.es}
• 关键词：GEMA ; Spanish guide for asthma management ; PBMCs ; peripheral blood mononuclear cells ; qRT-PCR ; quantitative real-time polymerase chain reaction ; PCA ; principal component analysis
• 刊名：Molecular Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：82
• 期：Complete
• 页码：34-45
• 全文大小：2801 K
• 卷排序：82

文摘

Gene-profiles able to differentiate asthma from allergic diseases have been defined. These groups of molecular biomarkers have been studied in non-invasive samples. Beside, we have described new potential biomarkers of severity in asthma. New tools to be assessed as diagnostic and/or therapeutic targets are provided.