刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:22 January 2017
年:2017
卷:482
期:4
页码:784-790
全文大小:666 K
卷排序:482
文摘
The pro-apoptotic ARF and BIM genes are specifically activated by deregulated E2F. Growth stimulation did not suppress E2F1 activation of the ARF or BIM genes. Constitutively active Akt/PKB did not suppress E2F1 activation of the ARF or BIM genes. The PI3K pathway does not suppress E2F regulation of the ARF and BIM genes.