Alpha-2-macroglobulin and heparin cofactor II and the vulnerability of carotid atherosclerotic plaques: An iTRAQ-based analysis

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• 作者：Jinmao Li^a ; ¹ ; Xi Liu^a ; ¹ ; Ying Xiang^a ; Xueying Ding^a ; Teng Wang^a ; Ying Liu^a ; Maojia Yin^a ; Changhong Tan^b ; Fen Deng^a ; Lifen Chen^a ; ^{lifen_chen@163.com}
• 关键词：Carotid atherosclerosis ; Proteomics ; iTRAQ ; Alpha-2-macroglobulin ; Heparin cofactor II
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：12 February 2017
• 年：2017
• 卷：483
• 期：3
• 页码：964-971
• 全文大小：1339 K
• 卷排序：483

文摘

Proteomic of pateints with different carotid plaque vulnerability were measured. Plasma α2M and HCII vary significantly with plaque vulnerability. α2M and HCII showed favorable efficiency in diagnosing plaque vulnerability.