刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:22 January 2017
年:2017
卷:482
期:4
页码:1135-1140
全文大小:994 K
卷排序:482
文摘
μ-Conopeptides typically inhibit voltage-gated Na+ channels. μ-PIIA and μ-SIIIA also block KV1.2 and KV1.6 voltage-gated K+ channels. Subtype specificity is mediated by the channel's pore and turret domain. μ-Conotoxins display marked target promiscuity.