Long noncoding RNA HULC promotes cell proliferation by regulating PI3K/AKT signaling pathway in chronic myeloid leukemia

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• 作者：Yinghao Lu ^{Yinghaolu123@163.com} ; Yan Li ^{Yanlimed@126.com} ; Xiao Chai ^{xiaochaixc@yeah.net} ; Qian Kang ^{qiankang1@outlook.com} ; Peng Zhao ^{pengzhao-1@outlook.com} ; Jie Xiong ^{jiexiong_vip@21CN.com} ; Jishi Wang ; ^{Jishiwangedu@outlook.com}
• 关键词：CML ; chronic myeloid leukemia ; TKIs ; tyrosine kinase inhibitors ; lncRNAs ; long non-coding RNAs ; HCC ; hepatocellular carcinoma ; HOX transcript antisense RNA ; HOTAIR M1 ; FBS ; fetal bovine serum ; FITC ; fluorescein isothiocyanate ; shRNA ; short hairpin RNA ; qRT-PCR ; quantitative real time PCR ; CP ; chronic phase ; AP ; accelerate phase ; BP ; blast phase
• 刊名：Gene
• 出版年：2017
• 出版时间：5 April 2017
• 年：2017
• 卷：607
• 期：Complete
• 页码：41-46
• 全文大小：698 K
• 卷排序：607

文摘

HULC aggrevates CML by regulating PI3K/AKT Inhibition of HULC enhances imatinib induced CML apoptosis HULC increased c-Myc and Bcl-2 by sequestering miR-200a-3p