Anti-obesity effect of radix Angelica sinensis and candidate causative genes in transcriptome analyses of adipose tissues in high-fat diet-induced mice

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• 作者：Tao Zhong ; Hao Zhang ; Xiaoyue Duan ; Jiangtao Hu ; Linjie Wang ; Li Li ; Hongping Zhang ; Lili Niu ; ^{niulili@sicau.edu.cn}
• 关键词：RAS ; Radix Angelica sinensis ; HFD ; high-fat diet ; DEGs ; differentially-expressed genes ; qPCR ; quantitative real-time PCR ; TCMs ; Chinese herbal medicines ; RIN ; RNA integrity number ; FPKM ; fragments per kilobase of transcript per million fragments mapped ; FDR ; false discovery rate ; KEGG ; Kyoto encyclopedia of genes and genomes ; APOA2 ; apolipoprotein A-II ; PNPLA3 ; patatin-like phospholipase domain containing A3 ; CIDEA ; cell death-inducing DNA fragmentation factor alpha-like effector A ; PCK1 ; phosph
• 刊名：Gene
• 出版年：2017
• 出版时间：30 January 2017
• 年：2017
• 卷：599
• 期：Complete
• 页码：92-98
• 全文大小：1307 K
• 卷排序：599

文摘

Transcriptome of adipose tissues from HFD induced mice with RAS supplementation were studied. Thirty-six DEGs were identified between DH group and HC mice. APOA2 gene is a candidate gene reducing body weight of obese mice.