Identification and molecular characterization of Escherichia coli bla_SHV genes in a Chinese teaching hospital

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• 作者：Mei Zhu^a ; Guangjian Yang^a ; Ailing Li^a ; Li Zong^a ; Zhaoguang Dong^d ; Junwan Lu^c ; Kaibo Zhang^c ; Cong Cheng^c ; Qingli Chang^a ; Xiuying Wu^b ; Jianchao Ying^a ; Xianneng Li^b ; Li Ding^a ; Haixiao Zheng^b ; Junping Yu^b ; Jun Ying^a ; Teng Xu^a ; Huiguang Yi^a ; Peizhen Li^a ; Kewei Li^a ; Songquan Wu^c ; Qiyu Bao^a ; ^{baoqy@genomics.cn} ; Junrong Wang^b ; ^{wangzhe96@163.com}
• 关键词：AmpC ; Cephalosporinase /Ampler class C β-lactamase ; ATCC ; American Type Culture Collection ; BLAST ; Basic Local Alignment Search Tool ; bp ; Base Pair ; CLSI ; Clinical and Laboratory Standards Institute ; E. cloacae ; Enterobacter cloacae ; E. coli ; Escherichia coli ; ESBL ; Extended-spectrum β-lactamase ; ITPG ; Isopropyl β-D-thiogalactoside ; kb ; kilobase ; K. pneumonia ; Klebsiella pneumonia ; MIC ; Minimum inhibitory concentration ; ORF ; Open reading frame ; PCR ; Polymerase Chain Reaction ; PFGE ; Pulsed-field
• 刊名：Gene
• 出版年：2017
• 出版时间：5 February 2017
• 年：2017
• 卷：600
• 期：Complete
• 页码：29-35
• 全文大小：508 K
• 卷排序：600

文摘

Four (0.8%) blaSHV β-lactamase-encoding genes were identified in Escherichia coli A novel blaSHV variant (blaSHV-195) was reported Two blaSHV-5 genes located in a 23 kb size of transferable plasmid, respectively Two wild strains (EC D2485 and EC D2487) which harbored blaSHV-5 and formed one cluster in PFGE analysis were clonally related