Vitamin D receptor gene FokI variant in diabetic foot ulcer and its relation with oxidative stress

详细信息    查看全文

• 作者：Negin Soroush^a ; Mania Radfar^a ; ^b ; ^{radfarma@tums.ac.ir} ; Armita Kakavand Hamidi^c ; Mohammad Abdollahi^d ; Mostafa Qorbani^e ; Farideh Razi^f ; Ensieh Nasli Esfahani^f ; Mahsa M Amoli^c ; ^{amolimm@tums.ac.ir}
• 关键词：AMPs ; antimicrobial peptides ; BMI ; body mass index ; bp ; base pair ; CI ; confidence intervals ; DFU ; diabetic foot ulcer ; DN ; diabetic nephropathy ; DR ; diabetic retinopathy ; EDTA ; ethylenediamine tetra acetic acid ; FFA ; free fatty acid ; FPG ; fasting plasma glucose ; FRAP ; ferric reducing ability of plasma ; HbA1C ; glycated hemoglobin ; IQR ; interquartile range ; MDA ; malondialdehyde ; OR ; Odds Ratio ; OS ; oxidative stress ; PCR-RFLP ; polymerase chain reaction-restriction fragment length polymorphism ; PUFA
• 刊名：Gene
• 出版年：2017
• 出版时间：30 January 2017
• 年：2017
• 卷：599
• 期：Complete
• 页码：87-91
• 全文大小：252 K
• 卷排序：599

文摘

Association of VDR rs2228570 T allele with DFU in Iranian patients with T2DM is found T allele is more frequent in patients with severe DFU based on Wagner classification Hyperglycemia causes generation of free radicals which leads to oxidative stress (OS) FokI variant correlation with TBARS level was found in patients carrying T allele