Ginger extract increases muscle mitochondrial biogenesis and serum HDL-cholesterol level in high-fat diet-fed rats

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• 作者：Soojung Oh^a ; ¹ ; Mak-Soon Lee^a ; ¹ ; Sunyoon Jung^a ; ¹ ; Seunghae Kim^a ; Hyeyoung Park^a ; Seonyoung Park^a ; Seog-Young Kim^a ; Chong-Tai Kim^b ; Young-Hee Jo^b ; In-Hwan Kim^c ; Yangha Kim^a ; ^{yhmoon@ewha.ac.kr}
• 关键词：ABCA1 ; ATP-binding cassette transporter A1 ; ApoA-1 ; apolipoprotein A-1 ; CYP7A1 ; 7 alpha-hydroxylase ; GEH ; high-fat diet containing 0.5% ginger extract ; GEL ; high-fat diet containing 0.25% ginger extract ; HDL-C ; high-density lipoprotein-cholesterol ; HF ; high-fat diet ; LCAT ; lecithin-cholesterol acyltransferase ; LDL-C ; low-density lipoprotein-cholesterol ; mtDNA ; mitochondrial DNA ; NRF ; nuclear respiratory factor ; PGC-1α ; peroxisome proliferator-activated receptor γ coactivator-1α ; PPAR ; peroxisome
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：29
• 期：Complete
• 页码：193-200
• 全文大小：843 K
• 卷排序：29

文摘

Effect of ginger extract was investigated in high-fat diet-fed rats. Treatment with ginger extract increased muscle mitochondrial biogenesis. Treatment with ginger extract elevated serum high-density lipoprotein-cholesterol level. Taken together, ginger extract might have beneficial effect against obesity-related metabolic disorders.