Rapid modulation of lipid metabolism in C57BL/6J mice induced by eicosapentaenoic acid-enriched phospholipid from Cucumaria frondosa

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• 作者：Lingyu Zhang^a ; Dan Wang^a ; Min Wen^a ; Lei Du^b ; Changhu Xue^a ; Jingfeng Wang^a ; Jie Xu^a ; ^{xujie9@ouc.edu.cn} ; Yuming Wang^a ; ^{wangyuming@ouc.edu.cn}
• 关键词：Short-term ; EPA-enriched phospholipid ; β-Oxidation ; Lipid metabolism ; Reversal
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：Complete
• 页码：28-35
• 全文大小：1063 K
• 卷排序：28

文摘

This study evaluates the time-dependent effects of EPA-PL from Cucumaria frondosa on lipid metabolism. EPA-PL strongly suppresses the hepatic TG accumulation (3 days) and the white adipose tissue mass (7 days). The mechanism of EPA-PL relies on upregulation of the β-oxidation in the liver and WAT. EPA-PL group remains higher hepatic DHA concentration during reversal.