AnMBR performed high efficient methanogenic degradation of sewage at 25 °C. Sludge yield was determined as 0.08 gMLVSS/gCODremoval. Toilet-paper cellulose with rich but refractory carbon source was fully degraded. Degradation of toilet paper could provide 26% of total methane production. Long SRT and co-digestion contributed to biodegradation of toilet-paper cellulose.