Automated Glycan Assembly of Oligo-N-Acetyllactosamine and Keratan Sulfate Probes to Study Virus-Glycan Interactions

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• 作者：Heung Sik Hahm¹ ; ² ; ⁵ ; Felix Broecker¹ ; ² ; ⁵ ; ⁶ ; Fumiko Kawasaki³ ; Mario Mietzsch⁴ ; ⁷ ; Regine Heilbronn⁴ ; Minoru Fukuda³ ; Peter H. Seeberger¹ ; ² ; ⁸ ; ^{peter.seeberger@mpikg.mpg.de}
• 关键词：automated glycan assembly ; AGA ; oligo-N-acetyllactosamine ; LacNAc ; keratan sulfate ; KS ; glycan microarray ; adeno-associated virus ; AAV
• 刊名：Chem
• 出版年：2017
• 出版时间：12 January 2017
• 年：2017
• 卷：2
• 期：1
• 页码：114-124
• 全文大小：2207 K
• 卷排序：2

文摘

LacNAc and keratan sulfate glycans were obtained by automated glycan assembly Linear, branched, and sulfated oligosaccharides up to hexamers were generated Glycan arrays revealed an interaction between keratan sulfate and AAV virus particles