Impact of maternally-derived antibodies against Salmonella enterica serovar Typhimurium on the bacterial load in suckling piglets

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• 作者：Jan Matiasovic ; ^{matiasovic@vri.cz} ; Hana Kudlackova ; Karolina Babickova ; Hana Stepanova ; Jiri Volf ; Ivan Rychlik ; Vladimir Babak ; Martin Faldyna
• 关键词：Pig ; Salmonella enterica serovar Typhimurium ; IgG ; IgA ; Colostrum
• 刊名：The Veterinary Journal
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：196
• 期：1
• 页码：114-115
• 全文大小：133 K

文摘

The significance of maternal immunity against non-typhoid Salmonella spp. acquired by piglets via colostrum and milk was evaluated in a Salmonella enterica serovar Typhimurium challenge experiment. Piglets from sows vaccinated with an experimental inactivated vaccine exhibited high levels of serum immunoglobulins G and A against S. Typhimurium 4 days after birth, just prior to experimental oral challenge. The S. Typhimurium load in the ileal and caecal wall of piglets 3 days after experimental inoculation was lower by a 2-log magnitude compared to unvaccinated controls. Such a vaccine, delivering colostral/lactogenic immunity to piglets thus has the potential to reduce the prevalence non-typhoid Salmonella spp. infection.