Biotransformation of isofraxetin-6-O-β-d-glucopyranoside by Angelica sinensis (Oliv.) Diels callus

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• 作者：Di Zhou^a ; Yuhua Zhang^b ; Zhe Jiang^c ; Yue Hou^d ; Kun Jiao^d ; Chunyan Yan^b ; ^{ycybridge@163.com} ; Ning Li^a ; ^{liningsypharm@163.com}
• 关键词：Biotransformation ; Isofraxetin-6-O-β-d-glucopyranoside ; Angelica sinensis (Oliv.) Diels callus ; Anti-neuroinflammation
• 刊名：Bioorganic & Medicinal Chemistry Letters
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：27
• 期：2
• 页码：248-253
• 全文大小：747 K
• 卷排序：27

文摘

Isofraxetin-6-O-β-d-glucopyranoside was deglycosylated using Angelica sinensis (Oliv.) Diels callus. A new coumarin was produced by the system with the stimulation of isofraxetin-6-O-β-d-glucopyranoside. Anti-inflammatory effects of transformed products were evaluated, and possible biosynthetic pathways were described.